http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110721317-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6923 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 |
| filingDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110721317-B |
| titleOfInvention | Carrier responding to pH value and reducing agent based on pseudorotaxane molecular structure and preparation method thereof |
| abstract | The invention relates to a carrier responding to pH and a reducing agent based on a pseudorotaxane molecular structure and a preparation method thereof, belonging to the field of material science. The carrier comprises hollow mesoporous inorganic oxide and pseudorotaxane molecules; the pseudorotaxane molecule comprises a chain molecule and a ring molecule with a hydrophobic cavity; one end of the chain molecule is a silane coupling agent, the other end of the chain molecule is a cysteine residue, and the silane coupling agent and the cysteine residue are connected through a disulfide bond; the silane coupling agent is connected with the hollow mesoporous inorganic oxide through a covalent bond; the ring-shaped molecules with hydrophobic cavities form a molecular barrier of the hollow mesoporous inorganic oxide; the cysteine residue can make the ring-shaped molecule with the hydrophobic cavity fall off under the acidic or alkaline condition, and the disulfide bond can be broken under the action of a reducing agent. The carrier disclosed by the invention can realize the release of the medicine in an acid-base environment and a reduction environment. |
| priorityDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.