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filingDate 2019-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110721215-B
titleOfInvention Ophthalmic aminopeptide injection and preparation method and application thereof
abstract The invention discloses an ophthalmic amino-peptide injection and a preparation method and application thereof. The preparation method comprises the following steps: taking the pig eyeball, smashing, extracting with ethanol solution twice and purified water once, filtering after extraction, and combining the filtrates to obtain a combined solution; concentrating the combined solution, heating to boil, filtering, adding activated carbon into the filtrate for adsorption treatment and titanium rod filter treatment, and cooling the filtrate to obtain a cooling liquid; collecting the permeate after the cooling liquid is subjected to ultrafiltration treatment, performing affinity chromatography treatment, and collecting the eluent of the target component; concentrating the eluent, blending, encapsulating and sterilizing to obtain the ophthalmic amino peptide injection. The ophthalmic amino peptide injection is also used for preparing a composition medicament for treating recurrent aphtha. According to the invention, by controlling the process parameters of the preparation method, the peptide content in the prepared ophthalmic amino peptide injection reaches 79.2%; the curative effect test of the recurrent aphtha shows that the composition medicament prepared by the ophthalmic amino peptide injection has the medicinal effect of treating the recurrent aphtha.
priorityDate 2019-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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