| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1287ca41e5a0309400cd066b808d2c6e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10052 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_861641334a1ce79349cdc48ecea1bb44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5d2852cd8bbf3801601d58d1a11184a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d4b85f8da50ef86cd6eff83d17d544
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c68411309dbd17e06f42c26a3afa7dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d6b2674803020bb07ee9add133430ee |
| publicationDate |
2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110714027-A |
| titleOfInvention |
An expression plasmid, cell line for packaging second-generation adenovirus and application thereof |
| abstract |
The invention discloses an expression plasmid, a cell line for packaging second-generation adenovirus and its application. The cell line of the present invention was deposited in the China Center for Type Culture Collection on May 8, 2019, and the deposit number is CCTCC NO: C2019111, and the classification name is human embryonic kidney transformed cell AY293-6015. The cell line of the present invention comprises the E4-ORF6/7 gene of adenovirus, and can be used to package the second-generation adenovirus with the deletion of the E4 gene to form complete and infectious second-generation adenovirus particles. The eukaryotic plasmid of the present invention replaces the CMV promoter commonly used in viral vectors with the RSV promoter, thereby reducing the occurrence probability of homologous recombination in virus cell packaging and reducing the formation of RCA. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022007800-A1 |
| priorityDate |
2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |