abstract |
The invention provides application of a specific lectin in preparing a test tool for identifying lung cancer and a device. For a sample taken from bronchoalveolar lavage fluid, the specific lectin is any one or any combination of the following lectins: MAL-II, RCA120, ECA, HHL, GSL-I, DBA, DSA, AAL; when the sugar chain structures identified by the lectins MAL-II, RCA120, ECA and HHL are obviously up-regulated, and the sugar chain structures identified by the lectins GSL-I, DBA, DSA and AAL are obviously down-regulated, judging that the sample is from a benign lung disease (BPD) patient; otherwise, the sample is judged to be from the lung cancer patient. The invention adopts bronchoalveolar lavage fluid as the object to be detected, and the sample is directly obtained from primary focus and adjacent tumor cells, so the sample has high organ specificity, can directly reflect the real condition of the body of a patient, and is safe and minimally invasive. |