Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42f8c05ebba982b49d4b553270d260d5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32332 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
2019-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cbcabbfdbf1e248615f9e74b4213ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1553b8411f2d8a74d234f1ebf3cc7868 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4391e2445301a569ef5db1853f336238 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5e72bfc7fa58baf3554b1d93173d73e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa2edbc4c7ceb6597164a1f1eda2e1fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08f2610c51cd27a78912d4a0e9e265a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57665c026e306d5ae40cfabb24240248 |
publicationDate |
2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110699380-A |
titleOfInvention |
A kind of EV71 virus nucleic acid plasmid and its construction method and application |
abstract |
The invention discloses an EV71 virus nucleic acid plasmid, wherein the EV71 virus nucleic acid plasmid includes the EV71 virus full-length cDNA sequence and the eukaryotic expression plasmid sequence. The present invention also provides a method for constructing the EV71 viral nucleic acid plasmid, which can package the live virus in tumor cells and induce tumor cell apoptosis. The present invention also provides the use of the EV71 viral nucleic acid plasmid for preparing a solid tumor-inhibiting drug. The EV71 viral nucleic acid plasmid of the present invention can enter into tumor cells to package live virus through a delivery vehicle, trigger the apoptosis of tumor cells, and effectively improve the oncolytic function of the virus. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235114-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235114-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111494433-A |
priorityDate |
2019-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |