http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110698539-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2019-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd7ff7c052ec4522139204996d1f392a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_407977ed37696f1eb9753fe9d4c6217e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd878b5e0f035355aab848b3f6293b84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54b57bac4dc591a67d08bc39da32f2c |
| publicationDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110698539-A |
| titleOfInvention | Mass spectrum probe for DPP-4 activity detection and preparation method and application thereof |
| abstract | The invention discloses a mass spectrometry probe for DPP-4 activity detection and application thereof. The mass spectrometry probe comprises a polypeptide with an amino acid sequence of Glu-Pro-Phe-Lys and a piperazine compound for modifying glutamic acid of the polypeptide. The mass spectrum probe provided by the invention is formed by connecting the polypeptide Glu-Pro-Phe-Lys which can be specifically identified by DPP-4 and a micromolecule piperazine compound with high spectrum response, not only can be specifically identified and enzyme-digested by DPP-4, but also has extremely high mass spectrum response, has high mass spectrum detection accuracy, can accurately reflect the activity of DPP-4, is suitable for detecting the enzyme activity in complex systems such as serum and the like, and is also suitable for screening compounds with DPP-4 inhibitory activity from complex systems such as traditional Chinese medicines and the like. |
| priorityDate | 2019-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 217.