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filingDate 2019-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d0a3902681592addd95b16bf47e594
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publicationDate 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110698451-A
titleOfInvention Substituted dibenzo[b,e]thio(oxy)heptacyclo-11(6H)-one compounds and preparation method thereof
abstract The invention relates to the field of medicinal chemistry, in particular to a substituted dibenzo[b,e]sulfur(oxy)heptacycle-11(6H)-ketone compound and a preparation method thereof. The preparation method includes the following steps: using phosphorus pentoxide as a cyclization catalyst, catalyzing substituted [(phenylthio(oxy)yl)methyl]benzoic acid to prepare substituted dibenzo[b,e]sulfur(oxy)heptacycle -11(6H)-ketones. The preparation method of the substituted dibenzo[b,e]sulfur(oxy)heptacycle-11(6H)-ketone compound of the present invention is safe and reliable, the solvent can be recycled and reused, the cost is low, the reproducibility is good, and the waste Acid and waste water are low, and the yield and purity of the obtained product are high.
priorityDate 2019-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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