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filingDate 2019-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110698380-B
titleOfInvention Lactam derivative and preparation method and application thereof
abstract The invention relates to a lactam derivative and a preparation method and application thereof. Compared with the prior art, the invention provides a lactam compound with a novel structure, and the compound and the composition thereof have obvious cancer cell proliferation inhibition activity (including but not limited to liver cancer cell line HepG2 and lung cancer cell line A549), and the activity of a plurality of compounds and the activity of a commercial drug adriamycin is in the same order of magnitude or better than the activity of the adriamycin; the compound can be prepared by reacting an N-substituted pyrrole compound, and the preparation method is convenient, rapid and efficient.
priorityDate 2019-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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