http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110683969-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-1809 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C273-18 |
filingDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110683969-B |
titleOfInvention | Urea derivative and synthetic method thereof |
abstract | The invention discloses a urea derivative and a synthesis method thereof, wherein the synthesis method comprises the steps of taking an amine compound as a raw material, adding an amine catalyst, introducing carbon dioxide gas into a reaction bottle, sequentially adding a solvent, hydrosilane and a Lewis acid catalyst into the reaction bottle in the atmosphere of the carbon dioxide gas, and carrying out reaction and catalytic synthesis by a one-pot method to obtain the urea derivative shown in the formula (I). The preparation method has the advantages of mild reaction conditions, simple and easily obtained raw materials, amine catalysts and Lewis acid catalysts, good substrate universality, simple and convenient post-treatment, good yield and the like. The invention also discloses application of the urea derivative shown in the formula (I) in the fields of synthesis and medicinal chemistry. |
priorityDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.