Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
filingDate |
2019-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2022-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110678484-B |
titleOfInvention |
Anti-PD-L1/anti-LAG3 bispecific antibody and use thereof |
abstract |
The present disclosure provides anti-PD-L1/anti-LAG3 bispecific antibodies capable of effectively blocking the interaction between PD-L1 and its receptor PD-1 and between LAG3 and its ligands (such as MHC class II molecules and FGL1) Interaction. The bispecific antibody may have high binding affinity for both PD-L1 protein (eg, human PD-L1 protein) and LAG3 protein (eg, human LAG3 protein). Also provided are antibodies and fragments that are specific for the PD-L1 or LAG3 protein alone, or that have additional specificity for one or more other antigens. |
priorityDate |
2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |