http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110669106-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2018-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110669106-B |
| titleOfInvention | Osteogenic targeting peptide modified chalcone derivative and preparation method and application thereof |
| abstract | The invention relates to the field of medicines, and particularly discloses an osteogenic targeting peptide modified chalcone for promoting bone formation of specific osteoporosis groupsThe structural formula of the chalcone derivative modified by the osteogenic targeting peptide is as follows: the preparation method of the chalcone derivative modified by the osteogenesis targeting peptide comprises the following steps: dissolving 2- (4-phenoxy-containing cinnamoyl) acetic acid, condensing agent and catalyst in organic solvent at room temperature, adding (DSS) 6 And (3) polypeptide reaction, and separation and purification are carried out after the reaction is finished. The chalcone derivative modified by the bone targeting peptide can effectively promote bone formation of osteoporosis patients of specific crowds, and also has good osteoblast targeting property, good water solubility and good safety; has wide application prospect in the aspect of preparing the medicine for promoting the bone formation of the osteoporosis specific population. |
| priorityDate | 2018-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.