http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110669044-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
| filingDate | 2019-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110669044-B |
| titleOfInvention | Donepezil-oxadiazole fusion compound and its preparation method and application |
| abstract | The invention discloses a donepezil-oxadiazole fusion compound, the structural formula of which is shown in formula (I), (II) (III) or (IV). The invention also discloses a preparation method of the above-mentioned donepezil-oxadiazole fusion compound and its Application in the preparation of therapeutic drugs for the treatment of Alzheimer's disease, the invention has a novel structure, has various activities such as inhibitor of cholinesterase, activation of Nrf2 pathway, etc., can increase the level of acetylcholine in the brain, and activate the anti-oxidative stress of cells reaction. |
| priorityDate | 2019-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.