http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110668946-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110668946-B |
| titleOfInvention | Compound Stybenpropol A and application thereof in preventing and treating atherosclerosis |
| abstract | The invention belongs to the technical field of medicines, and particularly discloses a compound Stybenpropol A and application thereof in improvement of Atherosclerosis (AS). Stybenproxol A is extracted from benzoin, and research results show that in Human Umbilical Vein Endothelial Cells (HUVECs) damaged by induction of tumor necrosis factors (TNF-alpha), Stybenproxol A can inhibit inflammatory injury of endothelial cells, increase nitric oxide secretion level, reduce levels of vascular adhesion molecules and proinflammatory factors, can remarkably inhibit inflammatory injury and apoptosis of TNF-alpha-induced HUVECs by inhibiting TNF-alpha-induced NF-kB activation and nuclear translocation and enhancing expression of anti-apoptotic protein Bcl-2, provides a new selection and approach for developing anti-atherosclerosis drugs, and has good application prospects. |
| priorityDate | 2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 218.