http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110665065-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-204 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0076 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 |
| filingDate | 2019-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110665065-B |
| titleOfInvention | Deferoxamine-loaded artificial periosteum and preparation method thereof |
| abstract | The invention discloses a DFO-loaded artificial periosteum and a preparation method thereof, belonging to the field of orthopedic implant materials, wherein degradable macromolecules are used as main raw materials, DFO molecules with osteogenesis functions are added, a DFO-macromolecule material blending artificial periosteum is prepared by an electrostatic spinning method, fiber blending and surface adsorption are carried out, and (or) polymer microspheres are added in a loading manner and then mixed with a degradable macromolecule material solution, and then DFO with amino groups is bonded to the surface of the DFO-macromolecule material blending artificial periosteum by selecting chemical bonds, so that the effect of slow and lasting release is achieved. The artificial periosteum has good osteogenesis activity, forms a barrier at the defect part, can effectively prevent invasion of pathogenic organisms and occurrence of heterotopic ossification, has good biocompatibility, mechanical strength and degradability, and can be used as a transplantation repair material for bone tissue defect. |
| priorityDate | 2019-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.