http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110664990-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110664990-B |
| titleOfInvention | Application of TRPC1 peptide molecule in preparation of medicine for treating inflammation caused by virus infection |
| abstract | The invention provides an application of a TRPC1 peptide molecule in preparing a medicament for treating inflammation caused by virus infection, belonging to the technical field of biological medicaments. Through research, the third extracellular domain polypeptide C1E3p of TRPC1 can obviously inhibit the co-localization of TRPC1 and HSV-1gD, so that the degree of entering the HSV-1 into cells is obviously reduced. A mouse basal keratitis (HSK) model is constructed through HSV-1 infection, HSK of a mouse is obviously relieved after the effect of C1E3p, H & E staining also shows that C1E3p can relieve inflammation symptoms of sclera, choroid and retina and retinal detachment, and the survival rate of the mouse is also obviously improved. Therefore, the polypeptide C1E3p has important significance for the research of medicaments for treating inflammations caused by HSV-1 and other virus infections of the same type. |
| priorityDate | 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 166.