http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110664784-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 |
filingDate | 2019-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110664784-B |
titleOfInvention | Composite nano drug delivery system and application thereof in gynecological tumor treatment |
abstract | The invention discloses a composite nano drug delivery system and application thereof in gynecological tumor treatment, comprising the following steps: (a) paclitaxel and curcumin composition as active ingredients; (b) miRNA-HA as a targeting material; (c) carboxylated magnetic mesoporous silica is used as a carrier. The invention uses the carboxylated magnetic mesoporous silicon dioxide as a drug carrier, on one hand, the larger drug loading capacity is ensured, and on the other hand, a modifiable point is provided for the modification of functional groups; by modifying the targeting material miRNA-HA, the targeting property of tumor cells of the carboxylated magnetic mesoporous silica nano drug delivery system and the targeting inhibition on gynecological tumor cells can be increased, and the inhibition rate on the migration and invasion of the tumor cells is improved. Meanwhile, the method has reasonable design, simple preparation process and wide application prospect, and lays a foundation for the design and development of a corresponding drug delivery system. |
priorityDate | 2019-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.