| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-624
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 |
| filingDate |
2018-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110662763-B |
| titleOfInvention |
Nav1.9 target polypeptide, antibody and antibody fragment combined with same and related pharmaceutical composition |
| abstract |
The invention provides an antibody or an antibody fragment thereof targeting a cell membrane voltage-gated sodium ion channel alpha subunit Nav1.9, wherein a specific combined target point is an S3-4 loop of a voltage sensor paddle of a II structural domain of the voltage-gated sodium ion channel alpha subunit. The antibody or the antibody fragment can inactivate the voltage sensor valve, so that sodium ions can not normally enter nerve cells, thereby achieving the effects of treating and relieving pain. |
| priorityDate |
2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |