http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110656073-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-05002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y504-02002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-04004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-01012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-06001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-182 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 |
| filingDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110656073-B |
| titleOfInvention | Recombinant bacterium for producing xanthine as well as construction method and application thereof |
| abstract | The invention discloses a recombinant strain for producing xanthine as well as a construction method and application thereof, belonging to the technical field of genetic engineering. The recombinant strain takes escherichia coli as an original strain, a transcription repressor gene purR, a phosphoglucose isomerase gene pgi, a phosphogluconate dehydratase gene edd, an adenylate succinate synthetase gene purA and a GMP synthetase gene guaA on an escherichia coli genome are knocked out respectively, and a PRPP synthetase gene prs with a D128A mutation, a K326Q mutation and a PRPP transamidase purF with a P410W double mutation are overexpressed. Meanwhile, the invention also provides a preparation method of the recombinant bacterium and a method for producing xanthine by using the recombinant bacterium. The invention realizes the high-efficiency biosynthesis of the xanthine in the recombinant bacteria for the first time. The recombinant strain is suitable for fermentation production of xanthine. |
| priorityDate | 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 903.