abstract |
The present invention relates to 2-aminopyrimidine derivatives, their preparation method and their application in medicine. Specifically, the present invention relates to a 2-aminopyrimidine derivative represented by the general formula (D-I), a preparation method thereof, a pharmaceutical composition containing the derivative, and its use as a therapeutic agent, especially as A Use of 2a receptor and/or A 2b receptor antagonists and use in the manufacture of a medicament for the treatment of a condition or disorder improved by inhibition of A 2a receptor and/or A 2b receptor, wherein the general formula Each substituent of (D-I) is as defined in the specification. |