| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4f1e152f24ad36296eedd141cb64c0e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2018-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a57e26d2f1590a23838c9468dba7960c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411de44fad0f94e7d8b7fc9b6f875af4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac49f39f9e4faeebc6f8371706825d5 |
| publicationDate |
2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110636868-A |
| titleOfInvention |
Regulation of gene expression through aptamer-mediated polyadenylation signal accessibility |
| abstract |
The present invention provides polynucleotide constructs for regulating gene expression by modulating the availability of one or more polyadenylation signals based on aptamers, and use of the constructs in response to ligands that bind aptamers. The presence or absence of methods to modulate gene expression. The polynucleotide construct contains a riboswitch comprising an aptamer and an effector stem-loop, wherein the effector stem-loop comprises a polyadenylation signal sequence. |
| priorityDate |
2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |