http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110632228-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-8631 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-86 |
| filingDate | 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110632228-B |
| titleOfInvention | Method for automatically realizing retention time drift correction and compound registration in UPLC-HRMS |
| abstract | A method for realizing retention time drift correction and compound registration in UPLC-HRMS includes the steps of simultaneously qualitatively and quantitatively representing chemical components in a complex sample through the UPLC-HRMS, automatically extracting compound information and constructing a mass spectrum spectrogram of the compound, screening compounds with rich ion information in the mass spectrum spectrogram to serve as markers, roughly correcting time drift among samples by adopting a dynamic time programming algorithm, then finely correcting EIC peaks, combining high-precision m/z values of the compounds according to corrected retention time, and realizing compound registration by utilizing a network link clustering algorithm. The method is suitable for analyzing large-batch samples based on UPLC-HRMS, and comprises the research fields of metabonomics, lipidomics, proteomics and the like, and complex samples such as food analysis, traditional Chinese medicine analysis and the like. |
| priorityDate | 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.