http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110627871-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae2be58a477cef66248d0dc28cb0ea82 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 |
| filingDate | 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5b1173a824d9bdecbd0c49f87a5067d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5bd07c493c7728fbfc59ec825abeb91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fd29fbbdeb2c33d34fb5c414d8af871 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc4e9ee6cd9e8f1858c5316635603203 |
| publicationDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110627871-A |
| titleOfInvention | Cationic bridged staple peptide and its application |
| abstract | The invention discloses a cationic bridged staple peptide. The staple peptide is a cyclic polypeptide with 10 to 20 amino acid residues, and has the following sequence and structural features: the polypeptide sequence can be P n ‑K c ‑ P m ‑K c ‑P i is a general formula; among them, P n , P m , and P i are polypeptide fragments with "n", "m" and "i" amino acid residues, n and i are natural numbers, and m is 3 or 6; where K represents lysine, and c represents the formation of a ring structure between two lysine side chain amino groups. The invention provides the preparation method and application of the cationic bridged staple peptide. The invention innovatively forms a ring structure on the side of the hydrophilic surface of the amphiphilic cationic antibacterial peptide to prepare a class of staple antibacterial peptide. This type of antimicrobial peptide has the following advantages: it has broad-spectrum antibacterial activity, especially has a significant inhibitory effect on clinical drug-resistant bacteria; it has a simple structure and is easy to synthesize; it has good biological stability; it can be applied to the prevention and treatment of human or animal infectious diseases or tumors. treat. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023056715-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112778403-A |
| priorityDate | 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.