http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110627696-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-09 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-56 |
| filingDate | 2019-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110627696-B |
| titleOfInvention | (Z) -4-difluoroalkyl-5-sulfanyl-4-pentenone derivative and preparation method thereof |
| abstract | A (Z) -4-difluoroalkyl-5-sulfanyl-4-pentenone derivative is prepared from alkyne thioether with structure of formula (II), monobromodifluoroacetate, iridium face-tri (2-phenylpyridine), alkali and solvent through mixing, radiating by blue light to form reaction system, and post-treating to obtain the (Z) -4-difluoroalkyl-5-sulfanyl-4-pentenone derivative with structure of formula (I). The invention realizes the series reaction of addition-hydrogen migration-non-cyclization of free radicals to non-terminal alkyne for the first time and realizes the stereoselective synthesis of the (Z) -4-difluoroalkyl-5-sulfanyl-4-pentenone derivative in one step. The method has the advantages of mild reaction conditions, wide substrate application range, good reaction yield, simple operation and capability of synthesizing the fluorine-containing pentanesThe synthesis of the ketene compounds provides a new approach. |
| priorityDate | 2019-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.