http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110615814-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C57-15 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-15 |
| filingDate | 2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110615814-B |
| titleOfInvention | Preparation method of tenofovir disoproxil hemifumarate |
| abstract | The invention provides a preparation method of tenofovir disoproxil hemifumarate. A method for preparing tenofovir disoproxil hemifumarate by a one-pot method. The generation of impurities in the synthesis process of tenofovir disoproxil is controlled by adding the water-binding agent, so that the intermediate tenofovir disoproxil is not required to be completely separated from a reaction system, the reaction treatment steps are saved, the loss in the process is reduced, and under the preferable process, the purity of the prepared tenofovir disoproxil hemifumarate is more than 99.0 percent, and the impurity tenofovir monofuroate is less than 0.1 percent; the total molar yield is stabilized at 77-85%. |
| priorityDate | 2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.