http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110615767-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 |
filingDate | 2019-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110615767-B |
titleOfInvention | Method for synthesizing 5-fluorocytosine |
abstract | The invention discloses a method for synthesizing flucytosine, and belongs to the field of nucleoside synthesis in organic chemistry. The reaction steps are as follows: by using N 4 Acyl protected cytosine is used as a raw material, organic carboxylic acid is used as a solvent, a one-step intermediate is obtained through direct fluorination, and 5-fluorocytosine is obtained through a removal reaction. The invention not only reduces the cost of raw materials, but also solves the problem of equipment corrosion caused by adopting the cytosine and hydrogen fluoride process, and simultaneously, the purity of the 5-fluorocytosine obtained by the method can reach more than 99.9 percent. |
priorityDate | 2019-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.