Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ca3568dc30a6560d19fcfcf0cc389ef |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-06 |
filingDate |
2019-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb8ad931d53e4506735b1dcb1d5fb6de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1e2ae695df3c78a93f55bafe7b9e2aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7ac5f8b7ee2f1213bb411721898659e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7e347191f008fdc5247690bdbcbd70c |
publicationDate |
2019-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110613844-A |
titleOfInvention |
A kind of mini combined adjuvant nanoparticle and its preparation method and application |
abstract |
The invention discloses a combined adjuvant nanoparticle prepared by self-assembly with an amphiphilic monomer molecule as a basic unit, wherein the amphiphilic monomer molecule is a hydrophobic adjuvant molecule and a hydrophilic adjuvant molecule The reaction is obtained. The stimulating effect of the combined adjuvant nanoparticles is stronger than that produced by the combined application of the hydrophilic adjuvant and the hydrophobic adjuvant in the free state. In addition, the combined adjuvant nanoparticles can also be used as nanocarriers to deliver antigens to antigen-presenting cells, promote the uptake of antigens by antigen-presenting cells, realize the co-delivery of antigens and adjuvants, and generate synergistic immune responses, which can greatly enhance anti-tumor effects. , tuberculosis and other vaccines immune efficacy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113521031-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111603556-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111603556-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021077770-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114288408-A |
priorityDate |
2019-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |