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filingDate 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110613735-B
titleOfInvention Application of NK cell exosome hsa-miR-9609 in antibiosis
abstract The invention discloses an exosome secreted by NK cells (aNK) activated by transmembrane IL-21, and application of various miRNAs contained in the exosome in antibiosis, neutralization and antitumor, and provides a new idea for treating bacterial infection and resisting tumors. The method comprises the following steps: (1) unlike antibiotic therapy, exosome antibiotics have lower side effects; (2) the antibacterial treatment effect can be enhanced by the combined use; (3) exosome can be stored at low temperature, miRNA can be artificially synthesized, cost is low, and large-scale production can be realized; (4) exosome and multiple miRNAs have inhibition effects on multiple bacteria, and have wide antimicrobial spectrum; (5) the miRNA acts on a signal path shared by multiple tumor cells, can inhibit multiple tumors, and has wide anti-tumor application.
priorityDate 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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