http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110606891-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2018-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110606891-B |
| titleOfInvention | A kind of antibody molecule against human CLDN18.2, antigen-binding fragment and its medical application |
| abstract | The invention discloses an anti-human CLDN18.2 antibody, its antigen-binding fragment and its medical use. Specifically, the present invention relates to murine antibodies comprising the CDR region of the anti-human CLDN18.2 antibody, chimeric antibodies, humanized antibodies, fully humanized antibodies, antibody-dependent cells comprising the antibodies and antigen-binding fragments thereof Toxicity (ADCC), complement-dependent cytotoxicity (CDC), killing effect on CLDN18.2 positive cells, inhibition of CLDN18.2 positive tumor growth, in vivo efficacy, and the combination of the anti-human CLDN18.2 antibody and its antigen The medicine of the fragment and its composition, and its use in tumor treatment, especially the treatment of CLDN18.2 positive tumor patients. |
| priorityDate | 2018-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 601.