http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110606811-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8bc4205cec55db4cb539b512b3d945b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 |
| filingDate | 2019-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e536754aae5fcb9204b1e7f1212bb6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e574133434a23b3bccec57e01f3c45f4 |
| publicationDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110606811-A |
| titleOfInvention | A kind of synthetic method of L-serine methyl ester hydrochloride |
| abstract | The invention discloses a synthesis method of L-serine methyl ester hydrochloride, comprising the following steps: initial reaction: adding L-serine into a solvent, cooling down to 0-10°C, adding thionyl chloride dropwise, and after the dropwise addition Raise the temperature to 35-40°C, react for 24-48 hours, and obtain a reaction mixture; wherein, the solvent is methanol A; cool and crystallize the above-mentioned reaction mixture, centrifuge to remove the solvent, and dry to obtain L-serine methyl ester hydrochloride; the centrifugal desolventization process The reclaimed methanol that takes off in is directly used as the mother liquor of the next step circulation; Apply mechanically: change the solvent described in the initial reaction into methanol B and reclaim the mixture of methanol. In the method of the present invention, by using the mother liquor in the previous step as a raw material, the amount of solvent used is small, and it is convenient to increase the yield of the final product; the solvent can be used indefinitely, no solid waste is generated, energy consumption and production costs are reduced, and efficiency is improved ; There is no need to recrystallize the product, which is convenient to shorten the production cycle and increase the yield. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113004160-A |
| priorityDate | 2019-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.