| abstract |
The invention discloses the application of a trillium steroid saponin in the preparation of a neuroprotective drug. The steroidal saponins DTCA and ETCA extracted from Trillium, as active ingredients, act as autophagy inducers that activate potent antioxidant effects, promote anti-oxidative stress responses through autophagy, increase cell viability, and reduce H 2 O 2 Induced PC12 cells damaged intracellular ROS levels, protected nerves, and exerted the potential to treat neurodegenerative diseases. |