Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0339 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-36 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate |
2019-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110596394-B |
titleOfInvention |
Application of histone H2A ubiquitination |
abstract |
The invention relates to an application of histone H2A ubiquitination, and particularly provides a kit, which comprises: a reagent for detecting the ubiquitination level of histone H2A or a functional analogue, for use in the diagnosis of a disease associated with aging in a mammal or in the determination of the prognostic effect. The application discloses the correlation between the ubiquitination of the histone H2A and the senescence-associated diseases for the first time, and the kit can be effectively used for the diagnosis of the senescence-associated diseases of mammals or the determination of the prognostic effect. |
priorityDate |
2018-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |