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filingDate 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110592223-B
titleOfInvention Application of a diagnostic and prognostic marker hsa_circRNA_012515 for NSCLC
abstract The invention discloses the application of a diagnostic and prognostic marker hsa_circRNA_012515 for NSCLC. The present study found that the expression level of hsa_circRNA_012515 was significantly increased in cancer tissues, NSCLC cells and drug-resistant cell lines of NSCLC patients (P<0.01). Moreover, patients with stage III–IV, lymph node metastasis and positive EGFR mutation highly expressed hsa_circRNA_012515. It indicated that hsa_circRNA_012515 could be used as a new biomarker for NSCLC and was closely related to the occurrence and development of NSCLC. In order to solve the problem of difficult early diagnosis of NSCLC, high degree of malignancy and poor prognosis of patients, it provides a new solution to the problem of lack of more sensitive and accurate diagnostic markers, and also provides timely diagnosis for NSCLC patients and guides clinical treatment.
priorityDate 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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