Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2018-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-110590952-B |
titleOfInvention |
High-affinity nano antibody for anti-CA 125 carbohydrate antigen and application thereof |
abstract |
The invention discloses a high-affinity nano antibody for resisting CA125 carbohydrate antigen, which has unique 3 complementary determining regions CDR1, CDR2 and CDR3, and also discloses application of the nano antibody in preparing tumor treatment medicines and tumor diagnosis reagents. The anti-CA 125 nano antibody provided by the invention has high specific recognition and binding capacity to CA125, has obvious ADCC effect on ovarian cancer cells, and can realize accurate imaging of tumors in mice. |
priorityDate |
2018-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |