| abstract |
The invention provides a process for removing polymers from human serum albumin, comprising the following steps: S1, component separation; S2, human serum albumin purification process; S3, pasteurization inactivation process; S4, chromatography process; S5 , Secondary pasteurization process; S6, aseptic filling process. In the human blood protein manufacturing process provided by the present invention, after the pasteurization process, the ion exchange chromatography process and the second pasteurization process are added, and the double pasteurization method is used to replace the traditional pasteurization method. Human serum albumin improves the quality of the product and effectively reduces the content of polymers in the product; by effectively removing the content of polymers and miscellaneous proteins in the product, the quality of human serum albumin is improved and adverse reactions during product use are reduced Occurrence, can improve the market competitiveness of human serum albumin, has a good market prospect. |