abstract |
The invention relates to the field of pharmaceutical synthesis and discloses a GLP-1 compound. The semaglutide analogs of the present invention are used for preparing a pharmaceutical composition for treating diseases, and the use of the pharmaceutical composition in preparing a medicament for treating at least one of the following diseases, the diseases include type II diabetes, sugar Impaired tolerance, type 1 diabetes, obesity, hypertension, metabolic syndrome, dyslipidemia, cognitive impairment, atherosclerosis, myocardial infarction, coronary heart disease, cardiovascular disease, stroke, inflammatory bowel syndrome and /or indigestion or gastric ulcer, liver fibrotic disease and pulmonary fibrotic disease. |