http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110590751-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04
filingDate 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110590751-B
titleOfInvention Preparation method of 5-maleimide chromone compound
abstract The invention discloses a preparation method of 5-maleimide chromone compounds, which comprises the following steps: in DCE solvent with [ Ru (p-cymene) Cl 2 ] 2 And AgNTf 2 As a catalyst, silver acetate as an additive, toThe maleimide compound and the chromone compound are taken as substrates to synthesize the 5-maleimide chromone compound. The method has the advantages of cheap and easily-obtained reaction raw materials, simple preparation method, low reaction cost, short reaction time, high yield and simple operation by using ruthenium as a catalyst, and is suitable for synthesizing different types of 5-maleimide chromone compounds. The method can be used for synthesizing a series of 5-maleimide chromone compounds, and the synthesized product can be used as an intermediate compound for further constructing complex active compounds; meanwhile, the compounds have great medicinal activity potential.
priorityDate 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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