http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110590706-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-023 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-023 |
| filingDate | 2019-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110590706-B |
| titleOfInvention | Preparation method of N-methylpyrrolidine |
| abstract | The invention relates to preparation of organic base of medicine and chemical raw materials, in particular to a preparation method of N-methylpyrrolidine, which comprises the following steps: a) under the catalysis of potassium iodide, 1, 4-dichlorobutane and methylamine water solution are mixed and reacted in an ether solvent to obtain N-methylpyrrolidine; the ether solvent can form hydrogen bond with methylamine, and the boiling point is larger than the azeotropic point of methylamine and water in the mixed system. The preparation method provided by the invention has the advantages of rich sources of raw materials, simple synthesis process route, no need of high-pressure reaction conditions, reduced equipment investment, simplified production management, reduced comprehensive cost, excellent economy and wide popularization prospect. Experimental results show that when the method is used for preparing the N-methylpyrrolidine, the preparation yield is more than 88 percent, and the product purity is more than 99 percent. |
| priorityDate | 2019-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.