http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110590602-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-59 |
| filingDate | 2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110590602-B |
| titleOfInvention | Resolution refining method of racemic citalopram diol |
| abstract | The invention discloses a resolution and refining method of racemic citalopram diol, which comprises the following steps: carrying out dissolving-crystallization operation on racemic citalopram diol and a resolving agent by alternately using a solvent A and a solvent B, and respectively collecting (S) -citalopram diol salt and (R) -citalopram diol salt obtained by crystallization each time; the (S) -citalopram diol salt and the (R) -citalopram diol salt collected each time were combined separately and further refined to give (S) -citalopram diol salt and (R) -citalopram diol salt. The method uses less than the theoretical use amount of the resolving agent, and achieves the effect of resolving (S) -citalopram diol reported in literatures. The (R) -citalopram dialkoxide is conveniently recycled by changing the solvent, and the discharge amount of three wastes is reduced. |
| priorityDate | 2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.