http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110585447-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 2019-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110585447-B |
titleOfInvention | Preparation method and application of aggregated luminescent nano-particle material capable of being used as sound sensitizer |
abstract | The invention discloses a preparation method and application of an aggregated luminescent nano-particle material capable of being used as a sound-sensitive agent, which comprises the following steps: (1) weighing tetra [ tetra- (4-aminophenyl) ] phenylethene (TAPE) and dissolving in chloroform to obtain a solution A; weighing liposome and dissolving the liposome in chloroform to obtain a solution B; adding the solution A into the solution B; (2) removing chloroform by rotary evaporation at normal temperature to obtain a TAPE-lipid nanoparticle lipid membrane C; (3) adding ultrapure water into a round-bottom flask to dissolve a TAPE-lipid nanoparticle lipid membrane C; (4) placing the mixture in an ultrasonic cell disruptor for ultrasonic treatment. The nano-particles prepared by the method solve the application of water-soluble AIE materials in organisms, develop novel functions, combine imaging function and ultrasonic activation function, realize the diagnosis-treatment integrated function of tumors, and have important application prospects in the fields of nano-medicine, disease diagnosis, treatment for overcoming the limitation of tumor hypoxia and the like. |
priorityDate | 2019-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.