http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110583573-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2570-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110583573-B |
| titleOfInvention | Construction and evaluation method of blood deficiency mouse model |
| abstract | The invention belongs to the technical field of model evaluation methods, and particularly relates to a model construction method and an evaluation method for blood-deficient mice. The method mainly solves the technical problems of low accuracy and poor specificity of the existing evaluation method of the blood deficiency model. The method adopts a metabonomics technology to analyze the change of endogenous metabolites in the spleens of mice in a blank control group and a model group, processes all mass spectrogram spectra through CD software to obtain integral data, analyzes the variation trend of integral mean values of the biomarkers in the spleens of the mice in the blank control group and the model group by combining the content statistics of 15 biomarkers, obtains the variation trend of the content of the metabolites in the spleens of the mice in blood deficiency, and accordingly evaluates the model of the mice in blood deficiency in a targeted manner. The method embodies the reasonability and scientificity of model replication, systematically and comprehensively expresses the body outline of mice in a blank control group and a model group, has the advantages of comprehensiveness, high efficiency and strong specificity, and provides a reliable evaluation method for research and development of new drugs and pharmacological research. |
| priorityDate | 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.