http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110577965-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H6-46 |
| filingDate | 2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110577965-B |
| titleOfInvention | Application of xCas9n-epBE base editing system in gene editing |
| abstract | The invention discloses the application of the xCas9n-epBE base editing system in gene editing. The xCas9n-epBE base editing system disclosed in the present invention includes xCas9n, PmCDA1, UGI and tRNA-esgRNA; the tRNA-esgRNA targets the target sequence; the tRNA-esgRNA is shown in formula I: tRNA-the target Sequentially transcribed RNA-esgRNA backbone (Formula I). It is proved by experiments that the xCas9n-epBE base editing system of the present invention realizes the editing of the target sequence in the plant genome, especially when the PAM sequence is NGT, NGA, NGG, GAA or GAT. Substitution of base C to base T. The xCas9n-epBE base editing system of the present invention has broad application prospects in plant or animal gene editing. |
| priorityDate | 2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1036.