http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110563583-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0238 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0244 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 |
| filingDate | 2018-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110563583-B |
| titleOfInvention | Method for asymmetrically catalyzing and synthesizing optically active 2-hydroxy-3, 3-dimethyl-4-oxobutyrate |
| abstract | The invention discloses a method for synthesizing optically active 2-hydroxy-3, 3-dimethyl-4-oxobutyrate by catalyzing asymmetric Aldol reaction of isobutyraldehyde and glyoxylate through chiral amino amide or enantiomer thereof. The method for asymmetrically catalyzing and synthesizing the optically active 2-hydroxy-3, 3-dimethyl-4-oxobutyrate is shown as the formula 1: adding isobutyraldehyde, glyoxylate, a chiral amino amide catalyst Cat and an additive into a reaction vessel containing a solvent, and stirring to obtain the product, namely the optically active 2-hydroxy-3, 3-dimethyl-4-oxobutyrate 1. The invention takes chiral amino amide or enantiomer thereof as an organic micromolecular catalyst, can catalyze asymmetric Aldol reaction of isobutyraldehyde and glyoxylate in a green and high-efficiency manner, and synthesize the 2-hydroxy-3, 3-dimethyl-4-oxobutyrate with high optical activity. |
| priorityDate | 2018-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.