http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110559288-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b407b0e38280e26e955c2bdb7993dc8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-365 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate | 2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1f9f4075d510757ecf27deae7399ae3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc6ac201169dbdf14da4061d3275d99c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79db5781e0f3de61d6e5ab64068f861 |
| publicationDate | 2019-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110559288-A |
| titleOfInvention | Application of arctigenin in preparing medicine for regulating macrophage differentiation |
| abstract | the invention discloses an application of arctigenin in preparing a medicine for regulating macrophage differentiation, which belongs to the technical field of traditional Chinese medicines, wherein in macrophages which are not derived from heart, the arctigenin can inhibit M1 type macrophages and M2c type macrophages from differentiating and promote M2a, M2b and M2d type macrophages from differentiating; arctigenin can inhibit CD86 in macrophage derived from heart + Macrophage, CCR2 + Macrophage differentiation and CD206 promotion + macrophage differentiation and inhibition LyC6 + Macrophage differentiation; in addition, arctigenin can reduce the number of monocytes in the heart and reduce cardiac CD14 + MPC-1 and ICAM-1 expression levels in monocytes. |
| priorityDate | 2019-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.