http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110551201-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51 |
| filingDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110551201-B |
| titleOfInvention | A novel cyclic peptide derived from bone morphogenetic protein 2, preparation method and application thereof |
| abstract | The invention relates to a novel BMP-2-derived cyclic peptide, a preparation method and an application thereof. The novel BMP-2-derived cyclic peptide is selected from one of the following cyclized polypeptides: the sequence is: 1. CKIPKASSVPTELSAISMLYLGPGGDWIVAC; 2. It has 80% homology with the polypeptide defined in 1; the preparation method of the novel bone morphogenetic protein 2-derived cyclic peptide and the application of the novel bone morphogenetic protein 2-derived cyclic peptide in the preparation of a composite material for promoting the repair of large volume bone defects . The beneficial effects of the present invention are as follows: the specially modified BMP2 cyclized polypeptide used in the present invention has the effect of efficiently inducing osteogenesis and can effectively promote the repair of large-volume bone defects; the specially modified BMP2 cyclized polypeptide used in the present invention is of human origin Polypeptide has good biocompatibility and no side effects such as immune rejection; the specially modified BMP2 cyclized polypeptide applied in the present invention can be loaded on various biological materials and has broad application prospects. |
| priorityDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.