http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110551081-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 |
| filingDate | 2019-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110551081-B |
| titleOfInvention | A method for extracting 10-deacetyl baccatin Ⅲ from Taxus chinensis |
| abstract | The invention discloses a method for extracting 10-deacetyl baccatine III from Taxus chinensis, and relates to the technical field of natural product extraction. The method comprises the following steps: (1) crushing; liquid nitrogen treatment; ammonia gas blasting treatment (2) Ultrasonic impurity removal of petroleum ether; (3) Extraction at high pressure and constant temperature with ethanol; Ultrasonic extraction with ethanol; (4) Concentration under reduced pressure, dissolving in acetone, filtering, and concentrating to obtain crude extract one; (5) Upper macroporous adsorption resin , washed with alkaline solution, washed with deionized water in turn, and then eluted with ethanol, collected the eluate, and concentrated to obtain crude extract two; (6) primary recrystallization: recrystallization using acetonitrile; (7) secondary recrystallization Crystallization: acetone/petroleum ether system is used for recrystallization; the present invention has strong operability, rationally sets each step and strictly controls operating parameters, and can obtain 10-deacetyl baccatine III with excellent purity and yield, and the purity reaches Above 99.3%, the yield is above 0.0242%. |
| priorityDate | 2019-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.