http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110548173-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| filingDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110548173-B |
| titleOfInvention | Preparation method of chemoembolization microsphere with microwave sensitization effect |
| abstract | The invention relates to a preparation method of chemoembolization microspheres with microwave sensitization effect, which comprises the steps of dispersing 8-12g of polyethanol microspheres in pure water, adding a hydroxyl activator to activate alcoholic hydroxyl groups of the polyethanol microspheres, wherein the mass ratio of tosyl chloride, 4-Dimethylaminopyridine (DMAP), triethylamine Et3N and the hydroxyl activator is 1:1.0-1.5:0.2-0.5:1.5, stirring at room temperature overnight, washing the polyethanol microspheres for a plurality of times by using the pure water, reacting the microspheres and the microwave sensitization compound at 60 ℃ for 10 hours, and finally dispersing the microspheres in the pure water again to absorb water and swell to obtain the chemoembolization microspheres with the microwave sensitization effect. The chemoembolization porous microsphere with the microwave sensitization effect provided by the invention is simple in preparation method and easy to operate in steps, and the prepared product has good microwave sensitization and temperature rise and tumor vascular embolization functions, is regular and spherical, and has high porosity, narrow particle size distribution and controllable particle size. |
| priorityDate | 2019-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.