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filingDate 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110548003-B
titleOfInvention Externally applied chondroitin sulfate nano composition as well as preparation method and application thereof
abstract The invention provides an externally applied chondroitin sulfate nano composition as well as a preparation method and application thereof, belonging to the field of medicines. The nano composition provided by the invention comprises the following components in percentage by mass: 5-100% of a nano-drug system, 5-40% of a humectant and 10-90% of a drug carrier, wherein the sum of the dosage of each component is 100%. The nano composition prepared by adopting the raw materials of each component with specific dosage has a structure similar to a biological membrane, comprises an oil phase and a water phase, is similar to a bilayer structure of skin, and can soften the horny layer of the skin, quickly permeate the horny layer and subcutaneous tissues on the surface of the skin, enter a joint cavity, be directly absorbed at a bone joint, maintain the concentration of a medicament required by treatment in the joint cavity for a long time, treat joint diseases, relieve pain and discomfort of the joint, and is convenient to administer, free of skin irritation and free of discomfort.
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