http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110547286-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0221 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
filingDate | 2018-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110547286-B |
titleOfInvention | Composite freezing solution and preparation method and application thereof |
abstract | The invention relates to a composite frozen stock solution as well as a preparation method and application thereof, and the composite frozen stock solution mainly comprises the following components: polyvinylpyrrolidone, trehalose, glycerol, Rock inhibitor and solvent. The composite cryopreservation liquid is prepared from the main components of polyvinylpyrrolidone, trehalose, glycerol, Rock inhibitor and the like, dimethyl sulfoxide is not required to be added, the risk of DMSO cytotoxicity is eliminated, the composite cryopreservation liquid can be used for long-term even permanent storage of adipose-derived stem cell glue at ultralow temperature, and active, safe and effective autologous fillers are provided for future fat transplantation. The fat stem cell gel frozen by using the composite freezing medium is transplanted into an animal body after 6 months of freezing, still shows good retention rate and tissue morphology after 3 months, and has no complications or adverse reactions. |
priorityDate | 2018-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.