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filingDate 2019-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110540837-B
titleOfInvention Preparation and application of a near-infrared fluorescent probe for hydrogen peroxide
abstract The present invention relates to the preparation and application of a hydrogen peroxide (H 2 O 2 ) near-infrared fluorescent probe. The structural formula of the probe is: The invention provides a preparation method for synthesizing the fluorescent probe with benzopyranonitrile-xanthene dye, potassium carbonate, 4-bromomethylphenylboronic acid pinacol ester, etc.; the fluorescent probe is a kind of A hydrogen peroxide fluorescent probe with near-infrared emission and large Stokes shift; firstly, the fluorescent probe exhibits high sensitivity to H 2 O 2 , and the fluorescence intensity is enhanced by 24 times; secondly, the fluorescent probe is sensitive to H 2 O 2 exhibits high selectivity and is not interfered by other reactive oxygen species, reactive nitrogen species, various ions, and biological thiols; moreover, the fluorescent probe reacts rapidly with H 2 O 2 , and the response time is within 30 minutes; in addition , the fluorescent probe is applied to the detection of hydrogen peroxide content in living cells.
priorityDate 2019-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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