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filingDate 2018-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee1a179000ce6aa2279be54340a2f9d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e1576dbf7703cb49ab2bad431d3b576
publicationDate 2019-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110538319-A
titleOfInvention A deformable nano vaccine and its preparation method and application
abstract The present invention provides a deformable nano-vaccine and its preparation method and application. The nano-vaccine includes a macromolecule-polypeptide assembly and a tumor antigen polypeptide, has monodispersity, and is spherical particles under physiological pH conditions. 100-200nm, endosomes change from spherical particles to 5-8μm two-dimensional lamellar structures in an acidic environment; the present invention combines nanotechnology and biological immunity, and prepares pH-responsive and self-assembled cells through complex experiments. The nano-vaccine has simple preparation process, ingenious principle, remarkable effect, and has broad application prospects and market value.
priorityDate 2018-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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